Vigilex Xendo DeutschlandXendo Deutschland

Contact info

Menne Zaalberg
T: +31 (0)71 524 40 00

Pieter de Wit
T: +31 (0)71 524 40 00

XPure SMB continuous ion exchange system

Xendo supports you to evaluate different techniques for:

  • Purification
  • Recovery
  • Isolation of products

Xendo SMB XPure engineering services

  • Range from lab, pilot to industrial scale SMB systems (up to 150m3 resin inventory)
  • Covers complete design cycle
    - characterization
    - sorbent screening
    - pilot testing (on site)
  • Covers sugars, food, food and non-food ingredients, (bio)pharmaceuticals, API’s and fine chemicals hydrometallurgy
  • Rely on state-of-the-art (good) engineering and automation practices and are automated to a steady state operating process producing constant high quality product streams

As SMB system supplier Xendo delivers two state-of-the-art technology concept of SMB: XPure-S and XPure-C.


The static SMB system XPure-S represents the by Xendo patented valve system with a zero dead leg concept.

Xendo offers SMB technology for product recovery and purification, comprising of

  • Feasibility studies
  • Developed simulation modeling software
  • Full scale design
  • Start-up, validation, maintenance and (process) service


  • Is not related to any manufacturer of resins
  • Applies originally manufactured components or any fabricates that are consistent with clients material standards
  • Optional elements
    - vessels and liquid distributors
    - (inter)connecting piping and auxiliary equipment

Xendo can cut your chromatography process costs by 20-50%

  • Less stationary phase (sorbent) media (resins) by higher utilization, that result in significantly
    - reduction in buffer consumption (countercurrent contact)
    - lower water consumption
    - less energy
  • Due to the modular characteristics of the valve blocks, Xendo can assemble these in a fast and efficient way

All this makes Xendo SMB technology attractive in terms of

  • Design
  • Cost
  • Delivery time
  • Smooth (after sales) services

Xendo has experience

  • Over 200 SMB studies
  • Over 30 of industrial projects realised

More details can be found in the brochure XPure or XPure-S.